bcbio-nextgen by bcbio

Validated, scalable, community developed variant calling, RNA-seq and small RNA analysis

created at Feb. 6, 2013, 11:14 a.m.

Python

86 +0

995 +0

353 +0

GitHub
hail by hail-is

Cloud-native genomic dataframes and batch computing

created at Oct. 27, 2015, 8:55 p.m.

Python

55 +0

984 +0

247 +0

GitHub
RNA-seq-analysis by crazyhottommy

RNAseq analysis notes from Ming Tang

created at Aug. 26, 2015, 7:37 p.m.

Python

78 +0

951 +4

300 +0

GitHub
bedtools2 by arq5x

bedtools - the swiss army knife for genome arithmetic

created at Dec. 9, 2013, 9:18 p.m.

C

58 +0

945 +1

287 +0

GitHub
prokka by tseemann

zap aquarius Rapid prokaryotic genome annotation

created at March 26, 2014, 7:19 a.m.

Perl

47 +0

852 +2

229 +2

GitHub
Flye by fenderglass

De novo assembler for single molecule sequencing reads using repeat graphs

created at March 17, 2016, 10:47 p.m.

C

30 +0

793 +1

168 +0

GitHub
freebayes by freebayes

Bayesian haplotype-based genetic polymorphism discovery and genotyping.

created at Oct. 13, 2010, 9:34 p.m.

C++

46 +0

792 +1

265 +0

GitHub
pysam by pysam-developers

Pysam is a Python package for reading, manipulating, and writing genomics data such as SAM/BAM/CRAM and VCF/BCF files. It's a lightweight wrapper of the HTSlib API, the same one that powers samtools, bcftools, and tabix.

created at Feb. 5, 2014, 8:38 p.m.

Cython

47 +0

789 +1

274 +1

GitHub
spades by ablab

SPAdes Genome Assembler

created at June 1, 2016, 3:06 p.m.

C++

32 +0

769 +3

139 +0

GitHub
ChIP-seq-analysis by crazyhottommy

ChIP-seq analysis notes from Ming Tang

created at June 12, 2015, 9:42 p.m.

Python

65 +0

755 +2

295 +0

GitHub
mosdepth by brentp

fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing

created at Aug. 24, 2017, 4:32 p.m.

Nim

22 +0

704 +1

101 +0

GitHub
bcftools by samtools

This is the official development repository for BCFtools. See installation instructions and other documentation here http://samtools.github.io/bcftools/howtos/install.html

created at July 12, 2013, 12:55 p.m.

C

48 +0

684 +2

240 +0

GitHub
bowtie2 by BenLangmead

A fast and sensitive gapped read aligner

created at Dec. 20, 2012, 7:25 p.m.

C++

32 +0

684 +1

159 +0

GitHub
poly by bebop

A Go package for engineering organisms.

created at May 29, 2020, 9 p.m.

Go

13 +0

676 -2

73 +0

GitHub
canu by marbl

A single molecule sequence assembler for genomes large and small.

created at Aug. 21, 2015, 3:10 a.m.

C++

54 +0

661 +0

179 +0

GitHub
igv by igvteam

Integrative Genomics Viewer. Fast, efficient, scalable visualization tool for genomics data and annotations

created at Feb. 11, 2012, 5:30 p.m.

Java

48 +0

647 +0

386 +0

GitHub
vcflib by vcflib

C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings

created at Sept. 22, 2010, 11:25 p.m.

C++

40 +0

628 +3

221 +0

GitHub
zindex by mattgodbolt

Create an index on a compressed text file

created at Feb. 26, 2015, 1:33 p.m.

C

23 +0

623 +1

37 +0

GitHub
hifiasm by chhylp123

Hifiasm: a haplotype-resolved assembler for accurate Hifi reads

created at May 9, 2019, 7:34 p.m.

C++

30 +0

559 +3

88 +0

GitHub
redun by insitro

Yet another redundant workflow engine

created at Nov. 4, 2021, 12:14 a.m.

Python

15 +0

536 +2

45 +0

GitHub